> Home > Research > Investigators > Research groups

  1. Megan Carey
    Neural Circuits and Behavior

    Eugenia Chiappe
    Sensorimotor Integration

    Bruno Costa-Silva
    Systems Oncology

    Gonzalo de Polavieja
    Collective Behavior

    Susana Lima

    Christian Machens
    Theoretical Neuroscience

    Zachary Mainen
    Systems Neuroscience

    Marta Moita
    Behavioral Neuroscience

    Eduardo Moreno
    Cell Fitness

    Michael Orger
    Vision to Action

    Joe Paton

    Leopoldo Petreanu
    Cortical Circuits

    Alfonso Renart
    Circuit Dynamics & Computation

    Christa Rhiner
    Stem cells and regeneration

    Carlos Ribeiro
    Behavior and Metabolism

    Adriana Sánchez Danés
    Cancer and Stem Cell Biology

    Noam Shemesh
    Preclinical MRI

    Maria Luísa Vasconcelos
    Innate Behavior

    Henrique Veiga-Fernandes

  1. Cancer and Stem Cell Biology

    Most tumours are heterogeneous at the cellular and (epi)genetic levels. This heterogeneity has been proposed to be responsible for tumour progression, metastasis and resistance to therapy. Our goal is to understand the contribution of the different tumour cell populations and genetic alterations to cancer progression and response to therapy. We do that by combining genetic lineage tracing, clonal analysis, imaging techniques, tumour organoid cultures and functional experiments in vivo and in vitro. We use the most frequent human cancer – basal cell carcinoma – and one of the most common pediatric cancers – medulloblastoma – as the models for our studies. Both types of cancer arise upon the constitutive activation of the Hedgehog signalling pathway.

Latest Publications